Medicinal value of peanut

① Hemostatic effect
It was initially found that oral peanuts could relieve bleeding symptoms in hemophilia patients, but it was later known that it was not only effective for hemophilia patients with type A (caused by lack of factor Ⅷ), but also more effective for hemophilia patients with type B (lack of factor IX), and it also had hemostatic effect for some other bleeding patients, but for severe bleeding patients, its effect was very poor. The effect of peanut peel is 50 times stronger than the peanut itself, and the effect is greatly reduced after frying (20 times weaker). A daily dose of 10 grams of skin extract is effective. It was originally proposed that hexane should be used for extraction, but now ethanol is used for extraction, that is, 200 grams of peanut rice is stir-fried, 2 kg of 96% ethanol is soaked for 96 hours, and 8 hours a day is vigorously stirred, standing, filtering, evaporating filtrate, residue is diluted to 100 grams with 96% ethanol, 40 drops are taken orally 4 times a day. The principle of its hemostatic effect has not been fully clarified, and it has no specific effect on hemophilia's blood coagulation defect, only to reduce bleeding symptoms, and does not increase the content of factors II-X in the plasma of patients. Peanut oil does not increase the contents of factors Ⅱ, Ⅶ and Ⅹ in rats fed high fat diet, and has no effect on human fibrinogen and factor Ⅷ. Peanut skin can shorten the coagulation time of hemophilia patients to normal. It has been proposed that its hemostasis is related to vasoconstriction, but it has not been proved. It is believed that its hemostasis is related to anti-fibrinolysis. The fibrinolytic activity of normal people can also be reduced by oral administration of peanut peel (from 100% to 40%). Peanut also has the same effect on rabbits fed normal and high cholesterol diet. This effect is either due to its increased action of fibrinolytic enzyme inhibitors, or due to its action against proteinolytic enzymes
The semi-refined trypsin inhibitor isolated from peanut can delay fibrinolysis, and its activity is greater than that of soybean trypsin inhibitor. The "euglobulin clot lysis time" was also significantly longer in hemophiliacs. It has been suggested that the clinical effect of peanut on hemophilia is related to the cholinolipids it contains. In addition, it has been reported that its extract can reduce the "re-calcification time" in hemophiliac patients, accelerate the activity of plasma thromboplastin, and improve thrombin elasticity. Large doses of trypsin inhibitors contained in it can delay thrombin production, and larger doses can slightly delay the "tissue thromboplastin time", but have no effect on the "thrombin time". It has also been proved in animals that the injection of peanut solution into normal dogs (10%2 ml/kg) can shorten the coagulation time, re-calcification time, improve the plasma tolerance to heparin, promote thrombosis and thrombin activity; If the fibrinolytic activity is significantly inhibited or the fibrinogen concentration is reduced, it can also increase the blood content of factor IX and Factor VIII. In vitro tests, it did not have any effect on accelerating blood clotting. It has been reported in the early years that the extract from peanut seeds, which removes fat and most proteins, has a heparin-like effect and can prevent blood clotting.
② Other effects Seeds contain a certain plant hemagglutinin, which can agglutinate human red blood cells treated with sialacidase, and belong to anti-P agglutinin. Flavus toxin is easily produced in peanuts, which can cause liver cancer. The endothelium of peanut contains anti-fibrinolytic enzyme, which can prevent all kinds of traumatic bleeding, liver bleeding, hemophilia and so on. However, peanuts are easy to be damp and mildew, and produce aflatoxin which is highly carcinogenic. Aflatoxin can cause toxic hepatitis, cirrhosis and liver cancer. This toxin is resistant to high temperatures, and cooking methods such as frying, frying, boiling, and frying cannot break it down. So we must pay attention not to eat moldy peanuts.